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IGF-1 LR3 (Long R3 Insulin-like Growth Factor-I) is a synthetic peptide consisting of 83 amino acids, mirroring the sequence of human IGF-I. It differs from native IGF-I by the substitution of an Arginine for the Glutamic Acid at position 3, along with a 13 amino acid extension peptide at the N-terminus. This modification renders Long R3IGF-I considerably more potent (2-3x) than IGF-1 LR3, as it exhibits lower affinity towards inactivation by IGF binding proteins, thus offering greater potential activity within the body.

IGF-1 LR3, comprising 70 amino acids in a single chain with three intramolecular disulfide bridges, shares a structural resemblance and size similarity with insulin. It belongs to the family of peptides known as growth factors and acts as a highly anabolic hormone produced both in the liver and peripheral tissues like skeletal muscle. Its release is stimulated by Human Growth Hormone (HGH), particularly after intense resistance training, facilitating muscle growth. While GH is recognized for its anabolic effects, IGF-1 LR3 is believed to be primarily responsible for GH's anabolic activities.

IGF-1 LR3 promotes muscle tissue growth by enhancing nitrogen retention and protein synthesis, fostering muscle development through hyperplasia and mitogenesis. Additionally, its effects extend beyond muscle building to lipid metabolism, aiding fat burning, and exerting neuroprotective and neurotropic properties, enhancing mental functions such as reflexes, memory, and learning ability. Moreover, IGF-1 contributes to connective tissue production and maintains proper bone density.

The benefits of IGF-1 LR3 include improvements in sex drive, reduction of belly fat, increased energy, enhanced skin elasticity, heightened endurance, accelerated wound healing, strengthened heart function, boosted immune system, better sleep patterns, improved eyesight, increased calcium retention, and enhanced protein synthesis.

Packaging: Each vial contains lyophilized product.

Dosage & administration:

Half life

50 – 70 hours


50-150mcg before each meal per day



Average Cycle Length

Indefinite and ongoing, since no user limit or cycle limit has ever been defined.

CAS Number



IGF-1 is only sold in kits of 10x Vials.(under no circumstances will singles be sold!)

IGF1-LR3 1mg

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