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Delta sleep-inducing peptide (DSIP) is a neuropeptide utilized by neurons in the brain for intercellular communication. Specifically, DSIP enhances activity and communication among neurons in the brain region responsible for sleep and rest. Recent research has indicated its involvement in sleep regulation, with some studies suggesting a connection to promoting slow-wave sleep (SWS) and inhibiting paradoxical sleep (PS), although other studies have found no correlation. Synthesized analogues of DSIP have shown stronger effects on sleep. Furthermore, DSIP may impact human lens epithelial cell function through the MAPK pathway, influencing various cellular processes such as proliferation, differentiation, and apoptosis.

Beyond simply enhancing feelings of well-being and restfulness, deep and restorative sleep has been demonstrated to significantly improve both physical and mental performance. During sleep, the body enters a highly anabolic state, with peak levels of growth hormone (GH), while insufficient rest can elevate levels of the catabolic hormone cortisol, affecting muscle repair and growth. DSIP has shown benefits beyond sleep regulation, including pain relief, anxiety alleviation, and normalization of sleep patterns. Its notable effects on sleep, such as mood enhancement, increased energy, and improved muscle growth and recovery, make it a forefront peptide.

Notably, DSIP is emerging as a potential treatment for delaying and managing symptoms associated with Parkinson’s and Alzheimer's diseases.

Dosage & administration:

Half life

30 minutes


500mcg 15 minutes before bed

Average Cycle Length


Anabolic #


Androgenic #



Estimated at 100%

Dsip 5mg sleep peptide

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